Comprehensive Guide to Peptide Dosing Plans - How to take BPC157 - TB500 - Mod-grf etc...
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by adding 13 amino acids to the N-terminal end of IGF-1 and by converting the glutamic acid at position 3 of IGF-1 to an arginine residue. Like IGF-1, IGF1-LR3 gives a signal for cell division and proliferation. Its main activity affects connective tissues such as muscles and bones, but it also promotes cell division in the liver, kidneys, nerves, skin, lungs and blood.
As a result, IGF1-LR3 stays in the bloodstream for much longer IGF-1 and the same dose of long IGF-1 is about 3 times stronger in terms of cell activation, and in the case of IGF1-LR3 muscles, it does not cause muscle cell growth, but increases the total number of cells muscle.
IGF1-LR3 increases fat metabolism indirectly through binding to both the IGF-1R and the insulin receptor. These actions increase the uptake of glucose from the blood by the cells of the muscles, nerves and liver. This causes a general drop in blood sugar, which then causes adipose tissue and the liver to break down glycogen and triglycerides, which in return gives us a reduction in total body fat and a reduction in energy
consumption for its breakdown. IGF1-LR3 reduces insulin levels as well as insulin requirements in patients with type 1 diabetes. In most cases this translates into a 10% reduction in insulin requirements in order to maintain the same blood sugar level.
IGF1-LR3 and other IGF-1 derivatives are able to counteract the negative effects of myostatin to protect muscle cells and prevent apoptosis. IGF1-LR3, thanks to its long half-life, does quite well at inhibiting myostatin and seems to work by activating a muscle protein called MyoD. MyoD is a protein activated by exercise or tissue damage and is responsible for muscle hypertrophy.
Looking at it from an anti-aging side, IGF1-LR3 promotes the repair and health of all tissues in our body (cow and pig studies) ongoing mice studies for the prevention of senile diseases such as dementia, muscle wasting and kidney disease.
Although IGF-1 is very similar to insulin (hence the name Insulin-like growth factor 1), its role is slightly different. Like insulin, IGF-1 is a transport hormone that helps nutrients (amino acids and glucose) reach the muscle cells. The cells themselves can then use these ingredients to synthesize new muscle tissue.
IGF-1 also works anabolic in bone, connective and intestinal tissues. This differs from insulin, which is a nutrient-transporting hormone in the broader sense of the word, because insulin transports nutrients not only to muscle tissue but also to many
other tissues throughout the body, so looking at it from a refined coke, insulin is not not selective at all, and this is what selectivity is all about.
Furthermore, IGF-1 plays a very unique and very specific number of roles in the human body, and this changes at every stage of human development. For example, it is responsible for various important factors of growth during childhood, and is also anabolic in adults. From a medical point of view, its use is mainly for the treatment of growth disorders, but since IGF-1 is a relatively new development in medicine, its experimental use in the treatment of other conditions continues to expand. Clinical research and application include, but are not limited to:
Dwarfism
Anti-aging
Neuropathy
Cancer
Stroke
There are many variants of IGF-1, IGF-1, IGF-1 LR3 and IGF-1 DES, and they all have different half-life and use-life properties that are associated with this period. For IGF-1 DES, the dosage range is 50 to 150 mcg per day. Due to a much shorter half-life than the LR3 variant, higher doses can be used without greater risk of long-term effects on the body, although caution should still be exercised.
MGF (PEG) Mechano Growth Factor - a mechanical growth factor
Also known as PEG-MGF, this peptide not only promotes muscle growth but also causes the formation of new muscle cells. IGF-1 is bound to polyethylene glycol (PEG) which distinguishes it from common mechanical growth factor. It follows that the MGF
half-life increases from minutes to several days. It is better to use PEG-MGF after training. The reason for this is the mechanical-sensitive nature of the MGF. This means that it is activated by a mechanical stimulus. The peptide facilitates faster recovery from muscle damage.
The list of the peptides mentioned is, of course, not exhaustive. There are many other types on the market, some of which are not necessarily beneficial for physique sports.
Peptides are dosed per weight, can (and even should) be mixed (GHRH + GHRP) when we don't have to be careful when natural burst is happening to get the best out of them.
It should be emphasized here that the amount of growth hormone released depends on what peptides we connect. An example of a combination that can provide very good results is GHRP-2 and MOD-GRF (1 - 29). It has been clinically proven that 100 mcg of both will result in a HGH burst comparable to more than 7iu in pharmacy hGH.
BPC - 157 (Body Protecting Compound)
L-Valine, glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L- prolylglycy l-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-
aspartyl-L-alanylglycyl-L-leucyl-; glycyl-L-alpha-glutamyl-L- prolyl-L-prolyl-L-prolylglycyllysyl-L-prolyl-L-alanyl-L-alpha- aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-L-valine, i jak widać jest łańcuch 15 aminokwasów.
As with all peptides, it should be handled carefully, saline should be poured down the side of the bottle, and if bacteriostatic water is available, it is preferable because then we do not need to keep it in the refrigerator and there will be more space for insulin and hGH, which We do not shake the solution in the bottle more and we handle it like an egg. The sufficient dosage, on which
I felt the effect of relief on the shoulder, was 250 mcg (I inserted it between the clavicle bone and the front akton, i.e. as close as possible to the place of the alleged injury, subcutaneously). It can be administered orally (we hold it in the mouth for about 2 minutes then swallow) or intramuscularly - here it will be known
- more painful, but where the joy of the injection coating and the peptide is, anyway, gets to the place where it is greatest demand.
Let's start with the fact that it is a measure not wrapped by a ban by WADA (at the moment!), It is not subject to any patents, so pharmaceutical companies cannot earn on it, and it is cheap as water, a lot of research that it works and is legal but let's get to the heart of the matter.
Our body produces BPC in very small amounts in gastric juices, where it serves to protect and "heal" the intestines, but when we grab a concentrated product, e.g. from BioLab, Peptides UK, it will have a very high level biological activity and theoretically (and I have already found out in practice) no matter where we stick it, it will start
repairing damaged tissues - all tissues
Teeth
Muscles
Bowels
Bones
Tendons
What has been proven not only in rats or IVF, but also in humans.
BPC also counteracts the side effects of non-steroidal inflammatory drugs such as diclofenac, naproxen,/22950504)
BPC is stable in gastric juice, it can induce an anabolic healing effect in the upper and lower gastrointestinal tract, has anti-ulcer properties and has a very good therapeutic effect against IBD, all without any side effects? Yeah buddy!
As proven in studies, BPC accelerates wound healing and, through interaction with nitric oxide, protects the endothelial tissues as well as forces increased angiogenze (for the less inquisitive - the process of capillary formation). Even in very poorly favorable conditions for regeneration, such as irritable bowel syndrome - during this action, thanks to BPC, the expression of genes responsible for cytokines and the production of growth factor, as well as the extracellular matrix,
i.e. collagen, is stimulated. Add to this the treatment of such problems as, for example, pathological anastomoses, and in this case - intestinal-intestinal fistulas (i.e. intestinal loop anastomosis), the administration of the BPC 157 peptide showed properties equal to between 15 - 40 mg of such antidepressants as, for example, imipramine - the first fully effective an antidepressant drug, used in 1957. It inhibits the reuptake of norepinephrine and serotonin from the synaptic cleft. It has a moderate peripheral and central anti-cholinergic effect and a weak antihistamine effect. 50% is absorbed from the gastrointestinal tract, metabolized in the liver to desipramine, an active metabolite that also has a psychotropic effect.
In tests with drugs from the diazepam group, such as e.g. valium BPC-157, it showed the following properties
Decreased tolerance to diazepam - lower dosage of drug
Reduced drug "withdrawal" symptoms
Anticonvulsant efficacy
Theoretically - the administration of this peptide simultaneously with diazepam may act postsynaptically, preventing the reduction of the level of benzodiazepine receptors, i.e. simply and to the point - it can be speculated that BPC157 has a beneficial effect on the natural homeostasis of the GABA receptor complex, and also strengthens GABAergic transmissions.
It has been known for a long time that BPC157 has a positive protective effect on the gastrointestinal tract and other internal organs (e.g. the heart), but it has also recently been proven that it has a protective effect on the dopaminergic system (in rats).
Blocks the side effects and motor stereotypes induced
by methamphetamine abuse
It interacts fully with the dopamine system - centrally and peripherally
It prevents certain stages of catalepsy (the symptom is caused by an increase in muscle tone with a simultaneous impairment or even complete blockage of the patient's motor functions. This stiffening is flexible, i.e. the
patient's body can be moved) and the formation of ulceration.
As a result, IGF1-LR3 stays in the bloodstream for much longer IGF-1 and the same dose of long IGF-1 is about 3 times stronger in terms of cell activation, and in the case of IGF1-LR3 muscles, it does not cause muscle cell growth, but increases the total number of cells muscle.
IGF1-LR3 increases fat metabolism indirectly through binding to both the IGF-1R and the insulin receptor. These actions increase the uptake of glucose from the blood by the cells of the muscles, nerves and liver. This causes a general drop in blood sugar, which then causes adipose tissue and the liver to break down glycogen and triglycerides, which in return gives us a reduction in total body fat and a reduction in energy
consumption for its breakdown. IGF1-LR3 reduces insulin levels as well as insulin requirements in patients with type 1 diabetes. In most cases this translates into a 10% reduction in insulin requirements in order to maintain the same blood sugar level.
IGF1-LR3 and other IGF-1 derivatives are able to counteract the negative effects of myostatin to protect muscle cells and prevent apoptosis. IGF1-LR3, thanks to its long half-life, does quite well at inhibiting myostatin and seems to work by activating a muscle protein called MyoD. MyoD is a protein activated by exercise or tissue damage and is responsible for muscle hypertrophy.
Looking at it from an anti-aging side, IGF1-LR3 promotes the repair and health of all tissues in our body (cow and pig studies) ongoing mice studies for the prevention of senile diseases such as dementia, muscle wasting and kidney disease.
Although IGF-1 is very similar to insulin (hence the name Insulin-like growth factor 1), its role is slightly different. Like insulin, IGF-1 is a transport hormone that helps nutrients (amino acids and glucose) reach the muscle cells. The cells themselves can then use these ingredients to synthesize new muscle tissue.
IGF-1 also works anabolic in bone, connective and intestinal tissues. This differs from insulin, which is a nutrient-transporting hormone in the broader sense of the word, because insulin transports nutrients not only to muscle tissue but also to many
other tissues throughout the body, so looking at it from a refined coke, insulin is not not selective at all, and this is what selectivity is all about.
Furthermore, IGF-1 plays a very unique and very specific number of roles in the human body, and this changes at every stage of human development. For example, it is responsible for various important factors of growth during childhood, and is also anabolic in adults. From a medical point of view, its use is mainly for the treatment of growth disorders, but since IGF-1 is a relatively new development in medicine, its experimental use in the treatment of other conditions continues to expand. Clinical research and application include, but are not limited to:
Dwarfism
Anti-aging
Neuropathy
Cancer
Stroke
There are many variants of IGF-1, IGF-1, IGF-1 LR3 and IGF-1 DES, and they all have different half-life and use-life properties that are associated with this period. For IGF-1 DES, the dosage range is 50 to 150 mcg per day. Due to a much shorter half-life than the LR3 variant, higher doses can be used without greater risk of long-term effects on the body, although caution should still be exercised.
MGF (PEG) Mechano Growth Factor - a mechanical growth factor
Also known as PEG-MGF, this peptide not only promotes muscle growth but also causes the formation of new muscle cells. IGF-1 is bound to polyethylene glycol (PEG) which distinguishes it from common mechanical growth factor. It follows that the MGF
half-life increases from minutes to several days. It is better to use PEG-MGF after training. The reason for this is the mechanical-sensitive nature of the MGF. This means that it is activated by a mechanical stimulus. The peptide facilitates faster recovery from muscle damage.
The list of the peptides mentioned is, of course, not exhaustive. There are many other types on the market, some of which are not necessarily beneficial for physique sports.
Peptides are dosed per weight, can (and even should) be mixed (GHRH + GHRP) when we don't have to be careful when natural burst is happening to get the best out of them.
It should be emphasized here that the amount of growth hormone released depends on what peptides we connect. An example of a combination that can provide very good results is GHRP-2 and MOD-GRF (1 - 29). It has been clinically proven that 100 mcg of both will result in a HGH burst comparable to more than 7iu in pharmacy hGH.
BPC - 157 (Body Protecting Compound)
L-Valine, glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L- prolylglycy l-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-
aspartyl-L-alanylglycyl-L-leucyl-; glycyl-L-alpha-glutamyl-L- prolyl-L-prolyl-L-prolylglycyllysyl-L-prolyl-L-alanyl-L-alpha- aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-L-valine, i jak widać jest łańcuch 15 aminokwasów.
As with all peptides, it should be handled carefully, saline should be poured down the side of the bottle, and if bacteriostatic water is available, it is preferable because then we do not need to keep it in the refrigerator and there will be more space for insulin and hGH, which We do not shake the solution in the bottle more and we handle it like an egg. The sufficient dosage, on which
I felt the effect of relief on the shoulder, was 250 mcg (I inserted it between the clavicle bone and the front akton, i.e. as close as possible to the place of the alleged injury, subcutaneously). It can be administered orally (we hold it in the mouth for about 2 minutes then swallow) or intramuscularly - here it will be known
- more painful, but where the joy of the injection coating and the peptide is, anyway, gets to the place where it is greatest demand.
Let's start with the fact that it is a measure not wrapped by a ban by WADA (at the moment!), It is not subject to any patents, so pharmaceutical companies cannot earn on it, and it is cheap as water, a lot of research that it works and is legal but let's get to the heart of the matter.
Our body produces BPC in very small amounts in gastric juices, where it serves to protect and "heal" the intestines, but when we grab a concentrated product, e.g. from BioLab, Peptides UK, it will have a very high level biological activity and theoretically (and I have already found out in practice) no matter where we stick it, it will start
repairing damaged tissues - all tissues
Teeth
Muscles
Bowels
Bones
Tendons
What has been proven not only in rats or IVF, but also in humans.
BPC also counteracts the side effects of non-steroidal inflammatory drugs such as diclofenac, naproxen,/22950504)
BPC is stable in gastric juice, it can induce an anabolic healing effect in the upper and lower gastrointestinal tract, has anti-ulcer properties and has a very good therapeutic effect against IBD, all without any side effects? Yeah buddy!
As proven in studies, BPC accelerates wound healing and, through interaction with nitric oxide, protects the endothelial tissues as well as forces increased angiogenze (for the less inquisitive - the process of capillary formation). Even in very poorly favorable conditions for regeneration, such as irritable bowel syndrome - during this action, thanks to BPC, the expression of genes responsible for cytokines and the production of growth factor, as well as the extracellular matrix,
i.e. collagen, is stimulated. Add to this the treatment of such problems as, for example, pathological anastomoses, and in this case - intestinal-intestinal fistulas (i.e. intestinal loop anastomosis), the administration of the BPC 157 peptide showed properties equal to between 15 - 40 mg of such antidepressants as, for example, imipramine - the first fully effective an antidepressant drug, used in 1957. It inhibits the reuptake of norepinephrine and serotonin from the synaptic cleft. It has a moderate peripheral and central anti-cholinergic effect and a weak antihistamine effect. 50% is absorbed from the gastrointestinal tract, metabolized in the liver to desipramine, an active metabolite that also has a psychotropic effect.
In tests with drugs from the diazepam group, such as e.g. valium BPC-157, it showed the following properties
Decreased tolerance to diazepam - lower dosage of drug
Reduced drug "withdrawal" symptoms
Anticonvulsant efficacy
Theoretically - the administration of this peptide simultaneously with diazepam may act postsynaptically, preventing the reduction of the level of benzodiazepine receptors, i.e. simply and to the point - it can be speculated that BPC157 has a beneficial effect on the natural homeostasis of the GABA receptor complex, and also strengthens GABAergic transmissions.
It has been known for a long time that BPC157 has a positive protective effect on the gastrointestinal tract and other internal organs (e.g. the heart), but it has also recently been proven that it has a protective effect on the dopaminergic system (in rats).
Blocks the side effects and motor stereotypes induced
by methamphetamine abuse
It interacts fully with the dopamine system - centrally and peripherally
It prevents certain stages of catalepsy (the symptom is caused by an increase in muscle tone with a simultaneous impairment or even complete blockage of the patient's motor functions. This stiffening is flexible, i.e. the
patient's body can be moved) and the formation of ulceration.
